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XRCC1 Antibody (Center)

XRCC1 Antibody (Center)

ArtNr	ABC-AP5545C-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Sarcoma Adenocarcinoma Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies By Organ Renal Cancer
Typ	Antibody Polyclonal
Applikationen	WB, FC, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Lamerdin, J.E., et al. Genomics 25(2):547-554(1995) Gyapay, G., et al. Nat. Genet. 7 (2 SPEC NO), 246-339 (1994): Thompson, L.H., et al. Mol. Cell. Biol. 10(12):6160-6171(1990) Thompson, L.H., et al. Genomics 5(4):670-679(1989)
NCBI	NP_006288.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA repair protein XRCC1,X-ray repair cross-complementing protein 1,XRCC1
Similar products	XRCC1, DNA repair protein XRCC1, X-ray repair cross-complementing protein 1
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Manufacturer - Category	Crown Antibodies; Primary Antibodies; Cancer; Metabolism
Manufacturer - Targets	This XRCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-435 amino acids from the Central region of human XRCC1.
Bio Background	The protein encoded by this gene is involved in theefficient repair of DNA single-strand breaks formed by exposure toionizing radiation and alkylating agents. This protein interactswith DNA ligase III, polymerase beta and poly (ADP-ribose)polymerase to participate in the base excision repair pathway. Itmay play a role in DNA processing during meiogenesis andrecombination in germ cells. A rare microsatellite polymorphism inthis gene is associated with cancer in patients of varyingradiosensitivity.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB24559
Gene Name	XRCC1 {ECO:0000303\|PubMed:2247054, ECO:0000312\|HGNC:HGNC:12828}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	69498
Antigen Source	HUMAN
Antigen Region	407-435
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:25 WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50
Antigen Type	Synthetic Peptide

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