Vergleich

MAGEC1 Antibody (C-term)

ArtNr ABC-AP6175a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products MAGEC1, Melanoma-associated antigen C1, MAGE-C1 antigen, Cancer/testis antigen 71, CT71
Lieferbar
Primary Accession
O60732
Antigen Type
Synthetic Peptide
Application
WB, IHC-P
Bio Background
MAGEC1 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, thus is about 800 residues longer than the other MAGE proteins. This gene is expressed in a significant proportion of tumors of various histological types, whereas it is silent in normal tissues, except testis. The function of this gene is unknown.
Bio References
Jungbluth, A.A., et al., Int. J. Cancer 99(6):839-845 (2002).
Chen, Y.T., et al., Proc. Natl. Acad. Sci. U.S.A. 95(12):6919-6923 (1998).
Lucas, S., et al., Cancer Res. 58(4):743-752 (1998).
Lim, S.H., et al., Eur. J. Haematol. 67 (5-6), 332-334 (2001).
Clonality
Polyclonal
Clone/Animal Names
RB2133/2134
Gene ID
9947
Gene Name
MAGEC1
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of MAGEC1 antibody (C-term) (Cat.# AP6175a) in K562 cell line lysates (35ug/lane). MAGEC1 (arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2
IHC-P
Dilution image 2
1:50~100
Other Accession
NP_005453
Isotype
Rabbit Ig
Calculated MW
123643
Antigen Region
849-880
Antigen Source
HUMAN
Target/Specificity
This MAGEC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 849-880 amino acids from the C-terminal region of human MAGEC1.
NCBI Accession
NP_005453.2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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