MMP13 Antibody (C-term)

ArtNr	ABC-AP6197a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Neuroscience Neuroinflammation Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Roy-Beaudry, M., et al., Arthritis Rheum. 48(10):2855-2864 (2003). Liacini, A., et al., Exp. Cell Res. 288(1):208-217 (2003). Hantke, B., et al., Biol. Chem. 384(8):1247-1251 (2003). Im, H.J., et al., J. Biol. Chem. 278(28):25386-25394 (2003). Tardif, G., et al., Osteoarthr. Cartil. 11(7):524-537 (2003).
NCBI	NP_002418.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Collagenase 3,3424-,Matrix metalloproteinase-13,MMP-13,MMP13
Similar products	MMP-13, MMP13, Collagenase 3, Matrix metalloproteinase-13, 3424-
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Cell Biology; Signal Transduction
Manufacturer - Targets	This MMP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-324 amino acids from the C-terminal region of human MMP13.
Bio Background	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB2094
Gene Name	MMP13
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	53820
Antigen Source	HUMAN
Antigen Region	295-324
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 WB: 1:500 IHC-P: 1:50~100 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

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