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MMP19 Antibody (C-term)

MMP19 Antibody (C-term)

ArtNr	ABC-AP6202a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MMP19, MMP18, RASI, Matrix metalloproteinase-19, Matrix metalloproteinase RASI, Matrix metalloproteinase-18, MMP-19, MMP-18, 3424-
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Primary Accession	Q99542
Antigen Type	Synthetic Peptide
Application	FC, WB, IHC-P
Bio Background	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of MMP19 has not been determined. This gene was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19).
Bio References	Sadowski, T., et al., Mol. Biol. Cell 14(11):4569-4580 (2003). Impola, U., et al., Int. J. Cancer 103(6):709-716 (2003). Mauch, S., et al., J. Immunol. 168(3):1244-1251 (2002). Stracke, J.O., et al., J. Biol. Chem. 275(20):14809-14816 (2000). Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999).
Clonality	Polyclonal
Clone/Animal Names	RB02035
Gene ID	4327
Gene Name	MMP19
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of hMMP19-R359 (Cat. #AP6202a) in K562 cell line lysates (35ug/lane). MMP19 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human breast carcinoma with MMP19 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	Flow cytometric analysis of K562 cells using MMP19 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	NP_002420
Isotype	Rabbit Ig
Calculated MW	57357
Antigen Region	344-373
Antigen Source	HUMAN
Target/Specificity	This MMP19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human MMP19.
NCBI Accession	NP_001259030.1; NP_002420.1

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