ST14 Antibody (C-term)

Synthetic Peptide

ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

Polyclonal

6768

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Anti-ST14 Antibody (C-term) at 1:1000 dilution + PC-3 whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 95 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

1:1000

WB

ST14 Antibody (C-term) (Cat. #AP6248a)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ST14 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

1:10~50

Rabbit Ig

826-855

This ST14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 826-855 amino acids from the C-terminal region of human ST14.