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PARP1 Antibody (N-term)

PARP1 Antibody (N-term)

ArtNr	ABC-AP6373A
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Flow Cytometry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, FC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Tao,Z., Biochemistry 47 (21), 5804-5813 (2008) Gao,R., Mol. Cancer Ther. 7 (5), 1246-1250 (2008) Schreiber,V., EMBO J. 11 (9), 3263-3269 (1992)
NCBI	NP_001609.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Poly [ADP-ribose] polymerase 1,PARP-1,ADP-ribosyltransferase diphtheria toxin-like 1,ARTD1,NAD(+) ADP-ribosyltransferase 1,ADPRT 1,Poly[ADP-ribose] synthase 1,PARP1,ADPRT,PPOL
Similar products	PARP1, PARP-1, PPOL, ADPRT, NAD(+) ADP-ribosyltransferase 1, Poly [ADP-ribose] polymerase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, ARTD1, ADP-ribosyltransferase diphtheria toxin-like 1
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Manufacturer - Category	Primary Antibodies; Cell Biology; Metabolism
Manufacturer - Targets	This PARP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-214 amino acids from the N-terminal region of human PARP1.
Bio Background	PARP1 is a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB14153
Gene Name	PARP1 {ECO:0000303\|PubMed:21680843, ECO:0000312\|HGNC:HGNC:270}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M
Calculated Molecular Weight	113084
Antigen Source	HUMAN
Antigen Region	183-214
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 WB: 1:1000 FC: 1:10~50
Antigen Type	Synthetic Peptide

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ABC-AP6373A-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 05.02.2026