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GCG Antibody (N-term)

GCG Antibody (N-term)

ArtNr	ABC-AP6515A
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	GLP-2, GCG, Glucagon, GLP-1, Glicentin, Glicentin-related polypeptide, Oxyntomodulin, Glucagon-like peptide 1, Incretin hormone, Glucagon-like peptide 1(7-37), Glucagon-like peptide 1(7-36), Glucagon-like peptide 2, OXM, GRPP, OXY, GLP-1(7-37), GLP-1(7-36)
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Primary Accession	P01275
Antigen Type	Synthetic Peptide
Application	IHC-P, FC, WB
Bio Background	GCG is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Bio References	Jacobo, S.M., J. Pharmacol. Exp. Ther. 330 (1), 283-293 (2009) Root-Bernstein, R.J. Mol. Recognit. 22 (3), 177-187 (2009)
Clonality	Polyclonal
Clone/Animal Names	RB19443
Gene ID	2641
Gene Name	GCG (HGNC:4191)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of GCG antibody (N-term) (Cat.# AP6515a) in mouse bladder tissue lysates (35ug/lane). GCG (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with GCG Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Legend image 3	Flow cytometric analysis of HepG2 cells using GCG Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	20909
Antigen Region	25-54
Antigen Source	HUMAN
Target/Specificity	This GCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human GCG.
NCBI Accession	NP_002045.1

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ABC-AP6515A-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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