INHA Antibody (N-term)

Primary Antibodies; Cancer; Signal Transduction; Cystine-knot cytokines

The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.

RB18802

Purified Rabbit Polyclonal Antibody (Pab)

39670

79-108

IF: 1:10~50
WB: 1:2000
IHC-P: 1:10~50
FC: 1:10~50