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EDNRB Antibody (C-term)

EDNRB Antibody (C-term)

ArtNr	ABC-AP6789B
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IF, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	EDNRB, Endothelin B receptor, ET-B, ET-BR, Endothelin receptor non-selective type, ETRB
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Primary Accession	P24530
Antigen Type	Synthetic Peptide
Application	FC, IF, IHC-P, WB
Bio Background	EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.
Bio References	MacClellan, L.R., et.al., Stroke 40 (10), E550-E557 (2009)
Clonality	Polyclonal
Clone/Animal Names	RB19285
Gene ID	1910
Gene Name	EDNRB (HGNC:3180)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Confocal immunofluorescent analysis of EDNRB Antibody (C-term)(Cat. #AP6789b) with 293 cell followed by Alexa Fluor®488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of EDNRB Antibody (C-term) (Cat. #AP6789b) in mouse cerebellum tissue lysates (35ug/lane). EDNRB (arrow) was detected using the purified Pab.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	EDNRB Antibody (C-term) (Cat. #AP6789b)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EDNRB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Legend image 4	EDNRB Antibody (C-term) (Cat. #AP6789b) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 4	FC
Dilution image 4	1:10~50
Other Accession	P21451; Q9N0W7; P35463; P48302; P28088; O62709
Predicted	B, Hs, Pig, Rb, Rat
Isotype	Rabbit Ig
Calculated MW	49644
Antigen Region	409-439
Antigen Source	HUMAN
Target/Specificity	This EDNRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human EDNRB.
NCBI Accession	NP_000106.1; NP_001116131.1; NP_001188326.1; NP_003982.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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