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PTPN11 Antibody (C-term)

PTPN11 Antibody (C-term)

ArtNr	ABC-AP6856B
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PTPN11, PTP2C, SHPTP2, Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, SH-PTP2, SH-PTP3, SHP-2, PTP-2C, PTP-1D, Shp2
Lieferbar
Primary Accession	Q06124
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic ansformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates.
Bio References	Rikova, K., et.al., Cell 131 (6), 1190-1203 (2007)
Clonality	Polyclonal
Clone/Animal Names	RB20780
Gene ID	5781
Gene Name	PTPN11
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of PTPN11 Antibody (C-term) (Cat. #AP6856b) in mouse bladder tissue lysates (35ug/lane). PTPN11 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human skeletal muscle reacted with PTPN11 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	PTPN11 Antibody (C-term) (Cat. #AP6856b) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	P41499; P35235; Q90687
Predicted	C, Rat
Isotype	Rabbit Ig
Calculated MW	68011
Antigen Region	520-547
Antigen Source	HUMAN
Target/Specificity	This PTPN11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 520-547 amino acids from the C-terminal region of human PTPN11.
NCBI Accession	NP_002825.3; NP_542168.1

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Menge: 400 ul

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