CBFB Antibody (Center)

Crown Antibodies; Primary Antibodies

CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.

RB21198

Affinity Purified Rabbit Polyclonal Antibody (Pab)

21508

61-90

IF: 1:10~50
WB: 1:1000
WB: 1:1000
IHC-P: 1:50~100
FC: 1:10~50