AKT2 Antibody (S474)

ArtNr	ABC-AP7029D
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Metabolism Diabetes Antibodies By Cell Type Carcinoma Hematology Lymphoma Myeloma Melanoma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	George, S., et al., Science 304(5675):1325-1328 (2004). Xu, X., et al., Oncol. Rep. 11(1):25-32 (2004). Shim, D., et al., Arch. Biochem. Biophys. 425(2):214-220 (2004). Li, X., et al., Gastroenterology 126(1):122-135 (2004). Vojtek, A.B., et al., Mol. Cell. Biol. 23(13):4417-4427 (2003).
NCBI	NP_001617.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	RAC-beta serine/threonine-protein kinase,Protein kinase Akt-2,Protein kinase B beta,PKB beta,RAC-PK-beta,AKT2
Similar products	AKT2, RAC-beta serine/threonine-protein kinase, Protein kinase Akt-2, Protein kinase B beta, RAC-PK-beta, PKB beta
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Cell Biology; Immunology; Metabolism; Neuroscience; Signal Transduction; Toll-Like receptor signaling; B cell receptor signaling; Fc gamma R-mediated phagocytosis; T cell activation; T cell receptor signaling; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling; Jak-STAT signaling KEGG; Apoptosis; Apoptosis signaling
Manufacturer - Targets	This AKT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-481 amino acids from human AKT2.
Bio Background	AKT2 is a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. AKT2 has been shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB11384
Gene Name	AKT2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M, Rat
Calculated Molecular Weight	55769
Antigen Source	HUMAN
Antigen Region	452-481
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:10~50 WB: 1:1000 IHC-P: 1:10~50
Antigen Type	Synthetic Peptide

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