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DNA PK (PRKDC) Antibody (C-term)

DNA PK (PRKDC) Antibody (C-term)

ArtNr	ABC-AP7053b
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Melanoma Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Goudelock, D.M., et al., J. Biol. Chem. 278(32):29940-29947 (2003). Ding, Q., et al., Mol. Cell. Biol. 23(16):5836-5848 (2003). Lucero, H., et al., J. Biol. Chem. 278(24):22136-22143 (2003). Calsou, P., et al., J. Mol. Biol. 326(1):93-103 (2003). Karpova, A.Y., et al., Proc. Natl. Acad. Sci. U.S.A. 99(5):2818-2823 (2002).
NCBI	NP_001075109.1,NP_008835.5
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA-dependent protein kinase catalytic subunit,DNA-PK catalytic subunit,DNA-PKcs,DNPK1,p460,PRKDC,HYRC,HYRC1
Similar products	PRKDC, DNPK1, DNA-PKcs, HYRC, HYRC1, DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, p460
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Manufacturer - Category	Primary Antibodies; Cell Biology; Signal Transduction
Manufacturer - Targets	This DNA PK (PRKDC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4075~4104 amino acids from the C-terminal region of human PRKDC.
Bio Background	The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 15269), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM]
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB3465/3466
Gene Name	PRKDC
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	469089
Antigen Source	HUMAN
Antigen Region	4075-4104
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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