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MAPK14 Antibody (T180/Y182)

MAPK14 Antibody (T180/Y182)

ArtNr	ABC-AP7226f
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MAPK14, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38 alpha, CSBP, CSBP1, CSBP2, CSPB1, SAPK2A, MAX-interacting protein 2, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, MAP kinase MXI2, MAP kinase p38 alpha, Stress-activated protein kinase 2a, MXI2, SAPK2a
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Primary Accession	Q16539
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Bio References	Cheung, P.C., et al., EMBO J. 22(21):5793-5805 (2003). Dean, J.L., et al., J. Biol. Chem. 278(41):39470-39476 (2003). Sun, A., et al., Exp. Neurol. 183(2):394-405 (2003). Yustein, J.T., et al., Oncogene 22(40):6129-6141 (2003). Frevel, M.A., et al., Mol. Cell. Biol. 23(2):425-436 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB15973
Gene ID	1432
Gene Name	MAPK14
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of anti-MAPK14 Antibody (T180/Y182) (Cat.#AP7226f) in mouse lung tissue lysates (35ug/lane). MAPK14 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	MAPK14 Antibody (T180/Y182)(Cat. #AP7226f) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MAPK14 Antibody (T180/Y182) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	P70618; P47811; Q9DGE2
Predicted	Zf, Rat
Isotype	Rabbit Ig
Calculated MW	41293
Antigen Region	158-192
Antigen Source	HUMAN
Target/Specificity	This MAPK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-192 amino acids from human MAPK14.
NCBI Accession	NP_001306.1; NP_620581.1; NP_620582.1; NP_620583.1

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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