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STK11 (LKB1) Antibody (N-term V34)

ArtNr ABC-AP7239D
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen WB, FC, IF
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products STK11, LKB1, Serine/threonine-protein kinase STK11, PJS, Liver kinase B1, Renal carcinoma antigen NY-REN-19, hLKB1
Lieferbar
Primary Accession
Q15831
Antigen Type
Synthetic Peptide
Application
IF, FC, WB
Bio Background
STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
Bio References
Mart, et al., J. Biotechnol. 115(1):23-34 (2005).
Shaw, R.J., et al., Proc. Natl. Acad. Sci. U.S.A. 101(10):3329-3335 (2004).
Suzuki, A., et al., Biochem. Biophys. Res. Commun. 324(3):986-992 (2004).
Hearle, N., et al., Genes Chromosomes Cancer 41(2):163-169 (2004).
Corradetti, M.N., et al., Genes Dev. 18(13):1533-1538 (2004).
Clonality
Polyclonal
Clone/Animal Names
RB11660
Gene ID
6794
Gene Name
STK11 (HGNC:11389)
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Confocal immunofluorescent analysis of STK11 (LKB1) Antibody (N-term V34)(Cat#AP7239d) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
Type image 1
IF
Dilution image 1
1:10~50
Legend image 2
Western blot analysis of STK11 Antibody (N-term V34) (Cat.# AP7239d) in Ramos cell line lysates. STK11 was detected using the purified Pab.
Type image 2
WB
Dilution image 2
1:1000
Legend image 3
STK11 (LKB1) Antibody (N-term V34) (Cat. #AP7239d) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3
FC
Dilution image 3
1:10~50
Other Accession
D4AE59; Q9WTK7; Q0GGW5
Predicted
C, M, Rat
Isotype
Rabbit Ig
Calculated MW
48636
Antigen Region
19-48
Antigen Source
HUMAN
Target/Specificity
This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human STK11 (LKB1).
NCBI Accession
NP_000446.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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