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BCOR Antibody (Center S1122)

BCOR Antibody (Center S1122)

ArtNr	ABC-AP7359c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BCOR, KIAA1575, BCL-6 corepressor, BCoR
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Primary Accession	Q6W2J9
Antigen Type	Synthetic Peptide
Application	WB, FC, IHC-P
Bio Background	BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs.
Bio References	Ghetu, A.F., Mol. Cell 29 (3), 384-391 (2008) Hilton, E.N., Hum. Mol. Genet. 16 (14), 1773-1782 (2007)
Clonality	Polyclonal
Clone/Animal Names	RB19040
Gene ID	54880
Gene Name	BCOR
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of BCOR Antibody (Center S1122) (Cat.# AP7359c) in 293 cell line lysates (35ug/lane). BCOR (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Anti-BCOR Antibody (Center S1122) at 1:500 dilution + Mouse liver whole tissue lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 192 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:500
Legend image 3	BCOR Antibody (Center S1122) (Cat.# AP7359c) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BCOR Antibody (Center S1122) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Legend image 4	Immunohistochemical analysis of paraffin-embedded Human Breast cancer section using Pink1(Cat#AP7359c). AP7359c was diluted at 1:50 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
Type image 4	IHC
Dilution image 4	1:50
Legend image 5	BCOR Antibody (Center S1122) (Cat. #AP7359c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 5	FC
Dilution image 5	1:10~50
Isotype	Rabbit Ig
Calculated MW	192189
Antigen Region	1107-1137
Antigen Source	HUMAN
Target/Specificity	This BCOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1107-1137 amino acids from the Central region of human BCOR.
NCBI Accession	NP_001116855.1; NP_001116856.1; NP_001116857.1; NP_060215.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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