MEN1 Antibody (S128)

ArtNr	ABC-AP7415a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Menin, MEN1, SCG2
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Primary Accession	O00255
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Menin (MEN1), a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known.
Bio References	Hashimoto, M., Int. J. Oncol. 33 (2), 333-340 (2008) Vidal, A., J Eur Acad Dermatol Venereol 22 (7), 835-838 (2008) Pieterman, C.R., Clin. Endocrinol. (Oxf) (2008)
Clonality	Polyclonal
Clone/Animal Names	RB0542
Gene ID	4221
Gene Name	MEN1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-MEN1 Antibody (S128) (Cat.#AP7415a) in Ramos cell line lysates (35ug/lane). MEN1 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with MEN1 Antibody (S128) (Cat.#AP7415a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q9WVR8; O88559; Q0P5I0; NP_000235
Predicted	B, M, Rat
Isotype	Rabbit Ig
Calculated MW	68023
Antigen Region	113-144
Antigen Source	HUMAN
Target/Specificity	This MEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-144 amino acids from human MEN1.
NCBI Accession	NP_000235.2; NP_570711.1; NP_570712.1; NP_570713.1; NP_570714.1; NP_570715.1; NP_570716.1

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