GIT1 Antibody (Y510)

ArtNr	ABC-AP7416a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	GIT1, CAT1, CAT-1, G protein-coupled receptor kinase-interactor 1, ARF GAP GIT1, ARF GTPase-activating protein GIT1, Cool-associated and tyrosine-phosphorylated protein 1, GRK-interacting protein 1
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Primary Accession	Q9Y2X7
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
Bio References	Sato, H., Biochem. Biophys. Res. Commun. 368 (1), 157-161 (2008) Jones, N.P., Mol. Cell. Biol. 27 (16), 5790-5805 (2007) Schmalzigaug, R., Cell. Signal. 19 (8), 1733-1744 (2007) Stockton, R., Mol. Biol. Cell 18 (6), 2346-2355 (2007)
Clonality	Polyclonal
Clone/Animal Names	RB15373
Gene ID	28964
Gene Name	GIT1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-GIT1 Antibody (Y510) (Cat.#AP7416a) in mouse cerebellum tissue lysates (35ug/lane). GIT1 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GIT1 Antibody (Y510) (Cat.#AP7416a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q9Z272; Q68FF6
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	84341
Antigen Region	487-517
Antigen Source	HUMAN
Target/Specificity	This GIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-517 amino acids from human GIT1.
NCBI Accession	NP_001078923.1; NP_054749.2

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