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IDH1 Antibody (N-term)

IDH1 Antibody (N-term)

ArtNr	ABC-AP7454A
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Sarcoma Myelofibrosis Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Astrocytoma By Organ Brain Cancer
Typ	Antibody Polyclonal
Applikationen	WB, FC, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Geisbrecht B.V., Gould S.J.J. Biol. Chem. 274:30527-30533(1999) Xu X., Zhao J., Xu Z.J. Biol. Chem. 279:33946-33957(2004) Bleeker F.E., Lamba S.Hum. Mutat. 30:7-11(2009)
NCBI	NP_001269315.1,NP_001269316.1,NP_005887.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Isocitrate dehydrogenase [NADP] cytoplasmic,IDH,Cytosolic NADP-isocitrate dehydrogenase,IDP,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase,IDH1,PICD
Similar products	IDH1, IDH, IDP, PICD, Cytosolic NADP-isocitrate dehydrogenase, Isocitrate dehydrogenase [NADP] cytoplasmic, Oxalosuccinate decarboxylase, NADP(+)-specific ICDH
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Manufacturer - Category	Primary Antibodies; Cancer; Metabolism; Signal Transduction
Manufacturer - Targets	This IDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the N-terminal region of human IDH1.
Bio Background	IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB18237
Gene Name	IDH1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Predicted Reactivity	B, Rat, Sh
Calculated Molecular Weight	46659
Antigen Source	HUMAN
Antigen Region	63-90
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IF: 1:10~50 WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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