Vergleich

CDK1 Antibody (T14)

ArtNr ABC-AP7517d
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products CDK1, CDC2, CDKN1, Cyclin-dependent kinase 1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase, CDC28A, P34CDC2
Lieferbar
Primary Accession
P06493
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
CDK1 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Bio References
Kramer, A., et al., Nat. Cell Biol. 6(9):884-891 (2004).
Dai, X., et al., J. Invest. Dermatol. 122(6):1356-1364 (2004).
Litvak, V., et al., Mol. Cell 14(3):319-330 (2004).
Shapira, M., et al., Cancer 100(8):1615-1621 (2004).
Chow, J.P., et al., J. Biol. Chem. 278(42):40815-40828 (2003).
Clonality
Polyclonal
Clone/Animal Names
RB07952
Gene ID
983
Gene Name
CDK1
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of CDK1(arrow) using rabbit polyclonal CDK1 Antibody (T14) (Cat.#AP7517d). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDK1 gene (Lane 2) (Origene Technologies).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CDK1 Antibody (T14) (Cat.#AP7517d), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:10~50
Other Accession
P39951; P11440; P23572; P13863; P48734; P24033; P35567
Predicted
X, B, C, D, M, Rat
Isotype
Rabbit Ig
Calculated MW
34095
Antigen Region
1-30
Antigen Source
HUMAN
Target/Specificity
This CDK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human CDK1.
NCBI Accession
NP_001777.1; NP_203698.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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