CLIC4 Antibody

ArtNr	ABC-AP7564a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CLIC4, Chloride intracellular channel protein 4, Intracellular chloride ion channel protein p64H1
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Primary Accession	Q9Y696
Antigen Type	Recombinant Protein
Application	IHC-P, WB
Bio Background	Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
Bio References	Singh, H., FEBS J. 274 (24), 6306-6316 (2007) Suh, K.S., J. Cell. Sci. 120 (PT 15), 2631-2640 (2007) Suh, K.S., Clin. Cancer Res. 13 (1), 121-131 (2007)
Clonality	Polyclonal
Clone/Animal Names	RB14721
Gene ID	25932
Gene Name	CLIC4
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of CLIC4 (arrow) using rabbit polyclonal CLIC4 Antibody (Cat.#AP7564a).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CLIC4 gene (Lane 2) (Origene Technologies).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CLIC4 antibody (Cat.#AP7564a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Isotype	Rabbit Ig
Calculated MW	28772
Antigen Source	HUMAN
Target/Specificity	This CLIC4 antibody is generated from rabbits immunized with recombinant human CLIC4 protein.
NCBI Accession	NP_039234.1

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Menge: 400 ul

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