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CLOCK Antibody (Center)

CLOCK Antibody (Center)

ArtNr	ABC-AP7582c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CLOCK, KIAA0334, bHLHe8, hCLOCK, Circadian locomoter output cycles protein kaput, BHLHE8, Class E basic helix-loop-helix protein 8
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Primary Accession	O15516
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	CLOCK belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within this protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.
Bio References	Sookoian, S., Am. J. Clin. Nutr. 87 (6), 1606-1615 (2008) Nakashima, A., Mol. Cell. Biol. 28 (12), 4080-4092 (2008) Marino, J.L., Epidemiology 19 (3), 477-484 (2008)
Clonality	Polyclonal
Clone/Animal Names	RB14279
Gene ID	9575
Gene Name	CLOCK
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of CLOCK Antibody (Center) (Cat. #AP7582c) in NCI-H460 cell line lysates (35ug/lane). CLOCK (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with CLOCK antibody (Center) (Cat.#AP7582c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q9WVS9; O08785
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	95304
Antigen Region	215-249
Antigen Source	HUMAN
Target/Specificity	This CLOCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-249 amino acids from the Central region of human CLOCK.
NCBI Accession	NP_001254772.1; NP_004889.1

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Menge: 400 ul

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