« Zurück
Startseite /
c ABL (ABL1) Antibody (C-term)

c ABL (ABL1) Antibody (C-term)

ArtNr	ABC-AP7694B
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ABL1, Tyrosine-protein kinase ABL1, Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Proto-oncogene c-Abl, p150, ABL, JTK7
Lieferbar
Primary Accession	P00519
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9; 22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
Bio References	Donaldson, L.W., et al., Proc. Natl. Acad. Sci. U.S.A. 99(22):14053-14058 (2002). Pisabarro, M.T., et al., J. Mol. Biol. 281(3):513-521 (1998). Nam, H.J., et al., Structure 4(9):1105-1114 (1996). Chissoe, S.L., et al., Genomics 27(1):67-82 (1995). Gosser, Y.Q., et al., Structure 3(10):1075-1086 (1995).
Clonality	Polyclonal
Clone/Animal Names	RB3083/3084
Gene ID	25
Gene Name	ABL1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	ABL1 Antibody (C-term) (Cat. #AP7694b) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ABL1 antibody detected the ABL1 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Isotype	Rabbit Ig
Calculated MW	122873
Antigen Region	851-881
Antigen Source	HUMAN
Target/Specificity	This c ABL (ABL1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 851-881 amino acids from the C-terminal region of human c ABL (ABL1).
NCBI Accession	NP_005148.2; NP_009297.2

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

ABC-AP7694B-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 400 ul

lieferbar

Lieferung vsl. bis 06.11.2025

Express-Lieferung: 14 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern