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FGR Antibody (N-term)

ArtNr ABC-AP7707A
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IF, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Carriero, M.V., et al., Biol. Chem. 383(1):107-113 (2002).
Katamine, S., et al., Mol. Cell. Biol. 8(1):259-266 (1988).
Nishizawa, M., et al., Mol. Cell. Biol. 6(2):511-517 (1986).
Cheah, M.S., et al., Nature 319(6050):238-240 (1986).
Tronick, S.R., et al., Proc. Natl. Acad. Sci. U.S.A. 82(19):6595-6599 (1985).
NCBI NP_001036194.1,NP_001036212.1,NP_005239.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Tyrosine-protein kinase Fgr,Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog,Proto-oncogene c-Fgr,p55-Fgr,p58-Fgr,p58c-Fgr,FGR,SRC2
Similar products FGR, Proto-oncogene c-Fgr, SRC2, Tyrosine-protein kinase Fgr, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, p55-Fgr, p58-Fgr, p58c-Fgr
Lieferbar
Manufacturer - Category
Primary Antibodies; Cancer; Signal Transduction; Anti-Kinome Antibodies; Immunity; Innate immunity; Chemokine signaling; Mitochondrion
Manufacturer - Targets
This FGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-33 amino acids from the N-terminal region of human FGR.
Bio Background
FGR is a member of the Src family of protein tyrosine kinases (PTKs). This protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. It localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB3095
Gene Name
FGR
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Calculated Molecular Weight
59479
Antigen Source
HUMAN
Antigen Region
3-33
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution
IF: 1:10~50
WB: 1:1000
WB: 1:1000
WB: 1:2000
IHC-P: 1:50~100
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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