PDX1 Antibody (N-term)

Primary Antibodies; Cancer; Cardiovascular; Developmental Biology; Metabolism; Signal Transduction

PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in the gene encoding PDX1 are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

RB10459

Affinity Purified Rabbit Polyclonal Antibody (Pab)

30771

40-69

WB: 1:1000
IHC-P: 1:10~50