DAXX Antibody (S495)

ArtNr	ABC-AP7773a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Cantrell, S.R., et al., J. Virol. 79(12):7792-7802 (2005). Greger, J.G., et al., J. Virol. 79(8):4610-4618 (2005). Chang, C.C., et al., J. Biol. Chem. 280(11):10164-10173 (2005). Beausoleil, S.A., et al., Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135 (2004). Gostissa, M., et al., J. Biol. Chem. 279(46):48013-48023 (2004).
NCBI	NP_001135441.1,NP_001241646.1,NP_001341.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Death domain-associated protein 6,Daxx,hDaxx,ETS1-associated protein 1,EAP1,Fas death domain-associated protein,DAXX,BING2,DAP6
Similar products	Daxx, DAXX, BING2, DAP6, Death domain-associated protein 6, ETS1-associated protein 1, Fas death domain-associated protein, EAP1, hDaxx
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Cell Biology; Microbiology; Amyotrophic Lateral Sclerosis (ALS); Viral process; Host-virus interaction; Apoptosis signaling
Manufacturer - Targets	This DAXX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from human DAXX.
Bio Background	DAXX is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, this protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, this protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB6869
Gene Name	DAXX
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	81373
Antigen Source	HUMAN
Antigen Region	473-502
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

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