MEK3 (MAP2K3) Antibody (N-term)

Primary Antibodies; Antibody Collections; Cancer; Cell Biology; Immunology; Signal Transduction; Amyotrophic Lateral Sclerosis (ALS); Anti-Kinome Antibodies; Toll receptor signaling; Toll-Like Receptor; Toll-Like receptor signaling; Apoptosis signaling

MAP2K3 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis.

RB0928

Purified Rabbit Polyclonal Antibody (Pab)

39318

15-45

WB: 1:1000
IHC-P: 1:50~100
IHC-P: 1:50~100