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CYP1A1 Antibody (Center)

CYP1A1 Antibody (Center)

Hersteller	Abcepta
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Specific against	other
Isotype	Ig
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IF, IHC-P
Menge	400 ul
Host	Rabbit
ArtNr	ABC-AP7993C
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Primary Accession	P04798
Antigen Type	Synthetic Peptide
Application	IHC-P, IF, WB
Bio Background	CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 gene has been associated with lung cancer risk.
Bio References	Delpisheh, A., Eur. J. Obstet. Gynecol. Reprod. Biol. 143 (1), 38-42 (2009) Zhuo, W., Cancer Invest. 27 (1), 86-95 (2009)
Clonality	Polyclonal
Clone/Animal Names	RB16935
Gene ID	1543
Gene Name	CYP1A1 {ECO:0000303\|PubMed:10681376, ECO:0000312\|HGNC:HGNC:2595}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Confocal immunofluorescent analysis of CYP1A1 Antibody (Center)(Cat#AP7993c) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of anti-CYP1A1 Antibody (Center) (Cat.#AP7993c) in mouse lung tissue lysates (35ug/lane). CYP1A1 (arrow) was detected using the purified Pab.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	CYP1A1 Antibody (Center) (Cat. #AP7993c)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP1A1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	58165
Antigen Region	252-280
Antigen Source	HUMAN
Target/Specificity	This CYP1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-280 amino acids from the Central region of human CYP1A1.
NCBI Accession	NP_000490.1

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ABC-AP7993C-datasheet.pdf

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Menge: 400 ul

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