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PCK1 Antibody (N-term)

PCK1 Antibody (N-term)

ArtNr	ABC-AP8093a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Metabolism Diabetes Glucose Homeostasis Antibodies Obesity Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Berger, K. et al. PLoS ONE. 4(3): e4671 (2009). Dunten, P., et al., J. Mol. Biol. 316(2):257-264 (2002). Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Deloukas, P., et al., Nature 414(6866):865-871 (2001). O'Brien, R.M., et al., Biochim. Biophys. Acta 1264(3):284-288 (1995). Ting, C.N., et al., Genomics 16(3):698-706 (1993).
NCBI	NP_002582.3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Phosphoenolpyruvate carboxykinase,cytosolic [GTP],PEPCK-C,PCK1,PEPCK1
Similar products	PCK1, PEPCK1, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], PEPCK-C
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Metabolism; Signal Transduction
Manufacturer - Targets	This PCK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-70 amino acids from the N-terminal region of human PCK1.
Bio Background	This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. A mitochondrial isozyme of the encoded protein also has been characterized.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB3644
Gene Name	PCK1 {ECO:0000303\|PubMed:8490617, ECO:0000312\|HGNC:HGNC:8724}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Calculated Molecular Weight	69195
Antigen Source	HUMAN
Antigen Region	40-70
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 WB: 1:1000 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

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Menge: 400 ul

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Lieferung vsl. bis 04.12.2025