ITPKA Antibody (N-term)

Synthetic Peptide

ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins(1, 3, 4, 5)P4. The activity of the inositol 1, 4, 5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.

Polyclonal

3706

Purified Rabbit Polyclonal Antibody (Pab)

Western blot analysis of anti-ITPKA Antibody (N-term) (Cat.#AP8166a) in mouse cerebellum tissue lysates (35ug/lane). ITPKA(arrow) was detected using the purified Pab.

1:1000

Rabbit Ig

1-30

This ITPKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ITPKA.