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Calcineurin (PPP3CA) Antibody (N-term)

Calcineurin (PPP3CA) Antibody (N-term)

ArtNr	ABC-AP8463a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PPP3CA, CAM-PRP catalytic subunit, CALNA, CNA, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calmodulin-dependent calcineurin A subunit alpha isoform
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Primary Accession	Q08209
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	PPP3CA is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. PPP3CA dephosphorylates HSPB1 and SSH1.
Bio References	Rodriguez, A., et al., J. Biol. Chem. 280(11):9980-9984 (2005). Shirane, M., et al., Nat. Cell Biol. 5(1):28-37 (2003). Bengoechea-Alonso, M.T., et al., Nitric Oxide 8(1):65-74 (2003). Huai, Q., et al., Proc. Natl. Acad. Sci. U.S.A. 99(19):12037-12042 (2002). Bennasser, Y., et al., Virology 303(1):174-180 (2002).
Clonality	Polyclonal
Clone/Animal Names	RB6001
Gene ID	5530
Gene Name	PPP3CA (HGNC:9314)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of anti-PPP3CA Pab (Cat. #AP8463a) in mouse kidney tissue lysate.PPP3CA(arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	P63329; P63328; P48452
Predicted	B, Rat
Isotype	Rabbit Ig
Calculated MW	58688
Antigen Region	21-51
Antigen Source	HUMAN
Target/Specificity	This Calcineurin (PPP3CA) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-51 amino acids from the N-terminal region of human Calcineurin (PPP3CA).
NCBI Accession	NP_000935.1; NP_001124163.1; NP_001124164.1

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Menge: 400 ul

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