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PON3 Antibody (N-term)

PON3 Antibody (N-term)

ArtNr	ABC-AP8595a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PON3, Serum paraoxonase/lactonase 3
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Primary Accession	Q15166
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	PON3 is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis.
Bio References	Precourt, L.P., et.al., Int. J. Biochem. Cell Biol. 41 (7), 1628-1637 (2009) Mackness, B., et.al., Curr. Opin. Lipidol. 13 (4), 357-362 (2002)
Clonality	Polyclonal
Clone/Animal Names	RB21339
Gene ID	5446
Gene Name	PON3
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of PON3 Antibody (N-term) (Cat. #AP8595a) in HepG2 cell line lysates (35ug/lane). PON3 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human hepatocarcinoma with PON3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	Flow cytometric analysis of HepG2 cells using PON3 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	39607
Antigen Region	10-38
Antigen Source	HUMAN
Target/Specificity	This PON3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-38 amino acids from the N-terminal region of human PON3.
NCBI Accession	NP_000931.1

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