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PTK2 Antibody (C-term)

PTK2 Antibody (C-term)

ArtNr	ABC-AP8614B
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IF, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PTK2, FAK, Focal adhesion kinase 1, Focal adhesion kinase-related nonkinase, Protein-tyrosine kinase 2, p125FAK, pp125FAK, FAK1, FRNK, PPP1R71, FADK 1, Protein phosphatase 1 regulatory subunit 71
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Primary Accession	Q05397
Antigen Type	Synthetic Peptide
Application	IF, FC, IHC-P, WB
Bio Background	PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.
Bio References	Calalb, M.B., et.al., Mol. Cell. Biol. 15 (2), 954-963 (1995) Polte, T.R. et.al., Proc. Natl. Acad. Sci. U.S.A. 92 (23), 10678-10682 (1995) Gervais, F.G., et.al., J. Biol. Chem. 273 (27), 17102-17108 (1998)
Clonality	Polyclonal
Clone/Animal Names	RB20776
Gene ID	5747
Gene Name	PTK2 (HGNC:9611)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Confocal immunofluorescent analysis of PTK2 Antibody (C-term)(Cat#AP8614b) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of PTK2 (arrow) using rabbit polyclonal PTK2 Antibody (C-term) (Cat. #AP8614b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PTK2 gene (Lane 2).
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human brain tissue reacted with PTK2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Legend image 4	PTK2 Antibody (C-term) (Cat. #AP8614b) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 4	FC
Dilution image 4	1:10~50
Other Accession	O35346; P34152
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	119233
Antigen Region	821-848
Antigen Source	HUMAN
Target/Specificity	This PTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 821-848 amino acids from the C-terminal region of human PTK2.
NCBI Accession	NP_001186578.1; NP_722560.1

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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