Vergleich

XPA Antibody (C-term)

ArtNr ABC-AP8784b
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB, FC, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products XPA, XPAC, DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing protein
Lieferbar
Primary Accession
P23025
Antigen Type
Synthetic Peptide
Application
FC, IHC-P, WB
Bio Background
XPA is involved in DNA excision repair. It initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. This protein is required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
Bio References
States J.C., et.al., Hum. Mutat. 12:103-113(1998).
Clonality
Polyclonal
Clone/Animal Names
RB23644
Gene ID
7507
Gene Name
XPA
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of XPA Antibody (C-term) (Cat. #AP8784b) in NCI-H460 cell line lysates (35ug/lane). XPA (arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with XPA Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:50~100
Legend image 3
XPA Antibody (C-term) (Cat. #AP8784b) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3
FC
Dilution image 3
1:10~50
Isotype
Rabbit Ig
Calculated MW
31368
Antigen Region
221-250
Antigen Source
HUMAN
Target/Specificity
This XPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 amino acids from the C-terminal region of human XPA.
NCBI Accession
NP_000371.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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