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FPRL2 Antibody (Center)

FPRL2 Antibody (Center)

ArtNr	ABC-AP8793c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	FPR3, FPRH1, FPRL2, N-formyl peptide receptor 3, FMLP-related receptor II, Formyl peptide receptor-like 2, FMLP-R-II
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Primary Accession	P25089
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Bio References	Yang, D., et.al., J. Leukoc. Biol. 72 (3), 598-607 (2002)
Clonality	Polyclonal
Clone/Animal Names	RB21312
Gene ID	2359
Gene Name	FPR3
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of FPRL2 Antibody (Center) (Cat. #AP8793c) in NCI-H460 cell line lysates (35ug/lane). FPRL2 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human lung carcinoma reacted with FPRL2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	FPRL2 Antibody (Center) (Cat. #AP8793c) flow cytometry analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	39965
Antigen Region	307-333
Antigen Source	HUMAN
Target/Specificity	This FPRL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-333 amino acids from the Central region of human FPRL2.
NCBI Accession	NP_002021.3

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