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TNFSF11 Antibody (N-term)

ArtNr ABC-AP8895a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB, FC, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products CD254, TNFSF11, RANKL, soluble form, membrane form, ODF, OPGL, TRANCE, TNF-related activation-induced cytokine, Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, Osteoprotegerin ligand, Receptor activator of nuclear factor kappa-B ligand
Lieferbar
Primary Accession
O14788
Antigen Type
Synthetic Peptide
Application
FC, IHC-P, WB
Bio Background
TNFSF11 is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response.
Bio References
Wong, B.R., et.al., J. Exp. Med. 186 (12), 2075-2080 (1997)
Clonality
Polyclonal
Clone/Animal Names
RB21817
Gene ID
8600
Gene Name
TNFSF11
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of TNFSF11 Antibody (N-term) (Cat. #AP8895a) in HL-60 cell line lysates (35ug/lane). TNFSF11 (arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human skeletal muscle reacted with TNFSF11 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:50~100
Legend image 3
TNFSF11 Antibody (N-term) (Cat. #AP8895a) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3
FC
Dilution image 3
1:10~50
Isotype
Rabbit Ig
Calculated MW
35478
Antigen Region
1-30
Antigen Source
HUMAN
Target/Specificity
This TNFSF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TNFSF11.
NCBI Accession
NP_003692.1; NP_143026.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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