LDLR Antibody (Center)

Primary Antibodies; Cancer; Cardiovascular; Metabolism; Signal Transduction; Host cell receptor for virus entry; Viral entry into host cell; Host-virus interaction; Lysosome

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.

RB22886

Affinity Purified Rabbit Polyclonal Antibody (Pab)

X, B, Ha, Pig, Rb, Rat

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide