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TIMP3 Antibody (Center)

TIMP3 Antibody (Center)

ArtNr	ABC-AP9124c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TIMP-3, TIMP3, Tissue inhibitor of metalloproteinases 3, Metalloproteinase inhibitor 3, Protein MIG-5
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Primary Accession	P35625
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	TIMP3 is one of inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM).
Bio References	Jacobson, S.G., et.al., Nat. Genet. 11 (1), 27-32 (1995) Wick, M., et.al., Biochem. J. 311 (PT 2), 549-554 (1995)
Clonality	Polyclonal
Clone/Animal Names	RB21049
Gene ID	7078
Gene Name	TIMP3
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of TIMP3 Antibody (Center) (Cat. #AP9124c) in HepG2 cell line lysates (35ug/lane). TIMP3 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of TIMP3 Antibody (Center) Pab (Cat. #AP9124c) pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse NIH-3T3 cell line lysate. TIMP3 Antibody (Center) (arrow) was detected using the purified Pab.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human breast carcinoma reacted with TIMP3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Legend image 4	TIMP3 Antibody (Center) (Cat. #AP9124c) flow cytometric analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 4	FC
Dilution image 4	1:10~50
Other Accession	P48032; O97590; P39876; P61269; P79121; Q9TUL9
Predicted	B, Hs, Pr, Rb, Rat
Isotype	Rabbit Ig
Calculated MW	24145
Antigen Region	113-139
Antigen Source	HUMAN
Target/Specificity	This TIMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-139 amino acids from the Central region of human TIMP3.
NCBI Accession	NP_000353.1

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ABC-AP9124c-datasheet.pdf

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Menge: 400 ul

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