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MUTYH Antibody (Center)

MUTYH Antibody (Center)

ArtNr	ABC-AP9161c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IF
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MUTYH, MYH, A/G-specific adenine DNA glycosylase, MutY homolog, hMYH, 322-
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Primary Accession	Q9UIF7
Antigen Type	Synthetic Peptide
Application	IF, FC, WB
Bio Background	MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of AoxoG to CG by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.
Bio References	Kim C.J., et.al., Oncogene 23:6820-6822(2004). Isidro G., et.al., Hum. Mutat. 24:353-354(2004). Sieber O.M., et.al., N. Engl. J. Med. 348:791-799(2003).
Clonality	Polyclonal
Clone/Animal Names	RB17460
Gene ID	4595
Gene Name	MUTYH
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Confocal immunofluorescent analysis of MUTYH Antibody (Center) (Cat. #AP9161c) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of MUTYH Antibody (Center) (Cat. #AP9161c) in mouse lung tissue lysates (35ug/lane). MUTYH (arrow) was detected using the purified Pab.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	MUTYH Antibody (Center) (Cat. #AP9161c) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	60069
Antigen Region	341-367
Antigen Source	HUMAN
Target/Specificity	This MUTYH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the Central region of human MUTYH.
NCBI Accession	NP_001041636.1; NP_001041637.1; NP_001041638.1; NP_001041639.1; NP_001121897.1; NP_036354.1

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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