Survivin Antibody

Survivin antibody can be used for detection of survivin by Western blot at 1 µg/mL. An approximate 17 kDa band should be detected. Antibody can also be used for immunocytochemistry starting at 10 µg/mL. For immunofluorescence start at 10 µg/mL.

BIRC5;

Survivin Antibody: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP. Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.

BIRC5

16389

Survivin Antibody is affinity chromatography purified via peptide column.

Survivin antibody can be used for detection of survivin by Western blot at 1 µg/mL. An approximate 17 kDa band should be detected. Antibody can also be used for immunocytochemistry starting at 10 µg/mL. For immunofluorescence start at 10 µg/mL.

Survivin Antibody is supplied in PBS containing 0.02% sodium azide.