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Caspase-13 Antibody

ArtNr ABC-ASC10096
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Applikationen WB, ELISA, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Citations Humke EW, Ni J, Dixit VM. ERICE, a novel FLICE-activatable caspase. J Biol Chem 1998;273:15702-7 (WD0500)
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Caspase-13 Antibody: CASP13,Caspase-13,Evolutionary related interleukin-1-beta-converting enzyme,CASP-13,caspase 4,apoptosis-related cysteine peptidase
Similar products Caspase-13, caspase 4, CASP-13, Evolutionary related interleukin-1-beta-converting enzyme, Caspase-13 Antibody: CASP13, apoptosis-related cysteine peptidase
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Manufacturer - Applications
Caspase-13 antibody can be used for detection of caspase-13 by Western blot at 1 µg/mL. A 43 kDa band should be detected. Antibody can also be used for immunohistochemistry starting at 10 µg/mL.
Manufacturer - Category
Primary Antibodies
Manufacturer - Targets
CASP4;
Storage Conditions
Caspase-13 antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background
Caspase-13 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13. Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.
Clonality
Polyclonal
Gene Name
CASP13
Reactivity
H, M, Rat
Calculated Molecular Weight
43012
Antigen Source
Bos taurus
Purification
Caspase-13 Antibody is Ion exchange chromatography purified.
Antibody Form
Liquid
Application Notes
Caspase-13 antibody can be used for detection of caspase-13 by Western blot at 1 µg/mL. A 43 kDa band should be detected. Antibody can also be used for immunohistochemistry starting at 10 µg/mL.
Positive Control
HL60 Cell Lysate; Mouse Brain Tissue Lysate; Rat Brain Tissue Lysate
Buffer
Caspase-13 Antibody is supplied in PBS containing 0.02% sodium azide.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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