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IL-21 Receptor Antibody

IL-21 Receptor Antibody

ArtNr	ABC-ASC10143
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Cell Biology Cell Culture Cytokines Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Primary
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Parrish-Novak J, Dillon SR, Nelson A, et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature. 2000;408(6808):57-63. Ozaki K, Kikly K, Michalovich D, et al. Cloning of a type I cytokine receptor most related to the IL-2 receptor β chain. Proc Natl Acad Sci USA. 2000;97(21):11439-44. Asao H, Okuyama C, Kumaki S, et al. the common γ-chain is an indispensable subunit of the IL-21 receptor complex. J Immunol. 2001;167(1):1-5. Vosshenrich CA, Di Santo JP. Cytokines: IL-21 joins the γ(c)-dependent network.Curr Biol. 2001;11(5):R175-7.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	IL-21 Receptor Antibody: NILR,CD360,NILR,UNQ3121/PRO10273,Interleukin-21 receptor,Novel interleukin receptor,IL-21 receptor,interleukin 21 receptor
Similar products	NILR, IL-21 Receptor Antibody: NILR, CD360, UNQ3121/PRO10273, Interleukin-21 receptor, Novel interleukin receptor, IL-21 receptor, interleukin 21 receptor
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Manufacturer - Category	Primary Antibodies; Cancer; Immunology; Jak-STAT signaling KEGG
Manufacturer - Targets	IL21R;
Storage Conditions	IL-21 Receptor antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background	IL-21 Receptor Antibody: A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling. Both IL-21R and the gammac are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Clonality	Polyclonal
Gene Name	IL21R
Reactivity	H, M, Rat
Calculated Molecular Weight	59130
Antigen Source	Homo sapiens
Purification	IL-21 Receptor Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	IL-21 receptor antibody can be used for detection of IL-21 receptor by Western blot at 1 µg/mL. An approximately 60 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 10 µg/mL. For immunofluorescence start at 20 µg/mL.
Positive Control	Raji Cell Lysate; Rat Lung Tissue Lysate
Buffer	IL-21 Receptor Antibody is supplied in PBS containing 0.02% sodium azide.

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Menge: 100 ug

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