IL-23 Antibody

IL-23 antibody can be used for the detection of IL-23 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2 µg/mL. For immunofluorescence start at 20 µg/mL.

IL23A;

IL-23 Antibody: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-? from activated T cells, and can stimulate macrophages to produce TNF-? and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.

IL23A

20730

IL-23 Antibody is affinity chromatography purified via peptide column.

IL-23 antibody can be used for the detection of IL-23 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2 µg/mL. For immunofluorescence start at 20 µg/mL.

IL-23 Antibody is supplied in PBS containing 0.02% sodium azide.