IL-17 Antibody

ArtNr	ABC-ASC10794
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Neuroinflammation Antibodies Cell Biology Cell Culture Cytokines Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Primary
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Miossec P. Are T cells in rheumatoid synovium aggressors or bystanders? Curr. Opin. Rheumatol.2000; 12:181-5. Paunovic V, Carroll HP, Vandenbroeck K, et al. Crossed signals: the role of interleukin (IL)-12, -17, -23, and -27 in autoimmunity. Rheumatol.2008; 47:771-6. Steinman L. A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage. Nat. Med.2007; 13:139-145.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Manufacturer - Category	Primary Antibodies; Cancer; Immunology; Cystine-knot cytokines; Cytokine
Manufacturer - Targets	IL17A;
Storage Conditions	IL-17 antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background	IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-?B and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.
Clonality	Polyclonal
Gene Name	IL17A
Reactivity	H, M
Calculated Molecular Weight	17504
Antigen Source	Homo sapiens
Purification	IL-17 Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	IL-17 antibody can be used for the detection of IL-17 by Western blot at 1 - 2 µg/mL.
Positive Control	THP-1 Cell Lysate
Buffer	IL-17 Antibody is supplied in PBS containing 0.02% sodium azide.

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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