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ARL15 Antibody

ArtNr ABC-ASC10943
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Applikationen WB, ELISA, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Citations Pasqualato S, Renault L, and Cherfils J. ARF, ARL, ARP and SAR proteins: a family of GTP-binding proteins with a structural device for ‘front-back'communication. EMBO Rep.2002; 3: 1035-41.
Kahn RA, Volpicelli-Daley L, Bowzard B, et al. ARF family GTPases: roles in membrane traffic and microtubule dynamics. Biochem. Soc. Trans.2005; 33: 1269-72.
Kahn RA, Cherfils J, Elias M, et al. Nomenclature for the human Arf family of GTP binding proteins: ARF, ARL, and SAR proteins. J. Cell Biol.2006; 172: 645-50.
Calin GA, Trapasso F, Shimizu M, et al. Familial cancer associated with a polymorphism in ARLTS1. N. Engl. J. Med.2005; 352:1667-76.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Manufacturer - Applications
ARL15 antibody can be used for detection of Arl15 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL.
Manufacturer - Category
Primary Antibodies; Signal Transduction
Manufacturer - Targets
ARL15;
Storage Conditions
ARL15 antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background
ARL15 Antibody: ADP-ribosylation factors (ARFs) are highly conserved guanine nucleotide binding proteins that enhance the ADP-ribosyltransferase activity of cholera toxin. ARFs are important in eukaryotic vesicular trafficking pathways and they play an essential role in the activation of phospholipase D (PC-PLD). ARL15 (ADP-ribosylation factor-like 15), is a member of the ARF family of the Ras superfamily of small GTPases that are known to be involved in multiple regulatory pathways altered in human carcinogenesis. Other members of this protein family include ARL11, thought to be a tumor suppressor and may play a role in the regulation of apoptosis, ARL2 which plays an important role in microtubule dynamics and cell cycle progression, and ARL4, which may play a role in neurogenesis during embryonic development. The gene encoding ARL15 maps to chromosome 5p15 in humans. At least three isoforms of ARL15 are known to exist.
Clonality
Polyclonal
Gene Name
ARL15
Reactivity
H, M, Rat
Calculated Molecular Weight
22876
Antigen Source
Homo sapiens
Purification
ARL15 Antibody is affinity chromatography purified via peptide column.
Antibody Form
Liquid
Application Notes
ARL15 antibody can be used for detection of Arl15 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL.
Positive Control
K562 Cell Lysate
Buffer
ARL15 Antibody is supplied in PBS containing 0.02% sodium azide.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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