ANGPT2 Antibody

ArtNr	ABC-ASC11444
Hersteller	Abcepta
Menge	100 ug
Kategorie	Oncology Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Primary
Applikationen	WB, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Hu B and Cheng SY. Angiopoetin-2: Development of inhibitors for cancer therapy. Curr. Oncol. Rep. 2009; 11:111-6. Maisonpierre PC, Suri C, Jones PF, et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 1997; 277:55-60. Lobov IB, Brooks PC, Lang RA, et al. Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo. Proc. Natl. Acad. Sci. USA 2002; 99:11205-10. Bach F, Uddin FJ, Burke D, et al. Angiopoietins in malignancy. Eur. J. Surg. Oncol. 2007; 33:7-15.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
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Manufacturer - Applications	ANGPT2 antibody can be used for detection of ANGPT2 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL.
Manufacturer - Category	Primary Antibodies; Cardiovascular; Developmental Biology
Manufacturer - Targets	ANGPT2; At least three isoforms of ANGPT2 are known to exist; this antibody will detect all three isoforms.
Storage Conditions	ANGPT2 antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background	ANGPT2 Antibody: Angiopoietin-2 (ANGPT2) is a member of the Ang family, a family of angiogenic factors that play major roles in angiogenesis during the development and growth of human cancers, but also during lymphangiogenesis. ANGPT2 is generally considered an antagonist of ANGPT1 and endothelial TEK tyrosine kinase (TIE-2, TEK). ANGPT2 disrupts the vascular remodeling ability of ANGPT1 and is thought to induce endothelial cell apoptosis, resulting in vessel regression. Expression of ANGPT2 has been linked to invasive and metastatic phenotypes of gliomas and other cancers.
Clonality	Polyclonal
Gene Name	ANGPT2
Reactivity	H, M, Rat
Calculated Molecular Weight	56919
Antigen Source	Homo sapiens
Purification	ANGPT2 Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	ANGPT2 antibody can be used for detection of ANGPT2 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL.
Positive Control	Human Liver Tissue Lysate
Buffer	ANGPT2 Antibody is supplied in PBS containing 0.02% sodium azide.

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Menge: 100 ug

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Lieferung vsl. bis 04.12.2025

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