NKX2-8 Antibody

ArtNr	ABC-ASC11449
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Primary
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Boettger T, Stein S, and Kessel M. The chicken NKX2.8 homeobox gene: A novel member of the NK-2 gene family. Dev. Genes Evol. 1997; 207:65-70. Kendall J, Liu Q, Bakleh A, et al. Oncogenic ccooperation and coamplification of developmental transcription factor genes in lung cancer. Proc. Natl. Acad. Sci. USA 2007; 104:16663-8. Hsu DS, Acharya CR, Balakumaran BS, et al. Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer. Proc. Natl. Acad. Sci. USA 2009; 106:5312-7.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	NKX2-8; NKX2-8 antibody is predicted to not cross-react with other NK2 homeobox family members.
Storage Conditions	NKX2-8 antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background	NKX2-8 Antibody: NKX2-8 (NK2 homeobox 8) is a member of a family of transcription factors that are involved in embryonic development and cell fate. It is expressed in the ventral foregut, the developing heart, the epithelial layers of the branchial arches and in the dorsal mesoderm. In conjunction with related protein, NKX2-5, NKX2-8 may play a role in cardiac embryonic development. NKX2-8 is also thought to be involved in lung development and is suspected of being an oncogene in lung cancer that is activated by way of gene amplification at chromosome 14q13.
Clonality	Polyclonal
Gene Name	NKX2-8
Reactivity	H, M, Rat
Calculated Molecular Weight	25866
Antigen Source	Homo sapiens
Purification	NKX2-8 Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	NKX2-8 antibody can be used for detection of NKX2-8 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 2.5 µg/mL.
Positive Control	Rat Liver Tissue Lysate
Buffer	NKX2-8 Antibody is supplied in PBS containing 0.02% sodium azide.

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Menge: 100 ug

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