Vergleich

VAMP7 Antibody

ArtNr ABC-ASC11508
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Applikationen WB, IF, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Citations Galli T, Zahraoui A, Vaidyanathan VV, et al. A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane of epithelial cells. Mol. Biol. Cell 1998; 9:1437-48.
Wang Y and Tang BL. SNAREs in neurons - beyond synaptic vesicle exocytosis. Mol. Membr. Biol. 2006; 23:377-84.
Advani RJ, Yang B, Prekeris R, et al. VAMP-7 mediates vesicular transport from endosomes to lysosomes. J. Cell Biol. 1999; 146:765-75.
Burgo A, Sotirakis E, Simmler MC, et al. Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner in neurite growth. EMBO Rep. 2009; 10:1117-24.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Manufacturer - Category
Primary Antibodies; Signal Transduction; Lysosome
Manufacturer - Targets
VAMP7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human VAMP7.
The immunogen is located within amino acids 20 - 70 of VAMP7.
Storage Conditions
VAMP7 antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background
VAMP7 Antibody: VAMP7 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family, localizing to late endosomes and lysosomes. VAMP7 is thought to mediate the fusion of endosomes to their target lysosomes as well as other exocytosis events during phagocytosis and neuritogenesis. VAMP7 interacts with the VPS9 ankyrin repeat protein VARP, a protein that localizes to early endosomes and thought to regulate endosome dynamics. Together with CD82, VAMP7 can modulate the signaling of EGFR by regulating its endocytosis from the plasma membrane.
Clonality
Polyclonal
Gene Name
VAMP7
Reactivity
H, M, Rat
Calculated Molecular Weight
24935
Antigen Source
Homo sapiens
Purification
VAMP7 Antibody is affinity chromatography purified via peptide column.
Antibody Form
Liquid
Application Notes
VAMP7 antibody can be used for detection of VAMP7 by Western blot at 0.5 - 1 μ g/mL. For immunofluorescence start at 20 μ g/mL.
Positive Control
Mouse Lung Tissue Lysate
Buffer
VAMP7 Antibody is supplied in PBS containing 0.02% sodium azide.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen