IL-15 Antibody

ArtNr	ABC-ASC11615
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Cell Biology Cell Culture Cytokines Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Primary
Applikationen	WB, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Bodnar A, Nizsaloczki E, Mocsar G, et al. A biophysical approach to IL-2 and IL-15 receptor function: localization, conformation and interactions. Immunol. Lett. 2008; 116:117-25. Ku CC, Murakami M, Sakamoto A, et al. Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science 2000; 288:675-8. Waldmann T, Tagaya Y, and Bamford R. Interleukin-2, interleukin-15, and their receptors. Int. Rev. Immunol. 1998; 16:205-26. Masuda A, Matsuguchi T, Yamaki K, et al. Interleukin-15 prevents mouse mast cell apoptosis through STAT6-mediate Bcl-xL expression. J. Biol. Chem. 2001; 276:26107-13.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
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Manufacturer - Applications	IL-15 antibody can be used for detection of IL-15 by Western blot at 1 - 2 µg/mL.
Manufacturer - Category	Primary Antibodies; Cancer; Immunology; Metabolism; Stem Cells
Manufacturer - Targets	IL15; At least two isoforms of IL-15 are known to exist.
Storage Conditions	IL-15 antibody can be stored at 4? for three months and -20?, stable for up to one year.
Bio Background	IL-15 Antibody: Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.
Clonality	Polyclonal
Gene Name	IL15
Reactivity	H, M, Rat
Calculated Molecular Weight	18086
Antigen Source	homo sapiens
Purification	IL-15 Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	IL-15 antibody can be used for detection of IL-15 by Western blot at 1 - 2 µg/mL.
Positive Control	Rat Spleen Tissue Lysate
Buffer	IL-15 Antibody is supplied in PBS containing 0.02% sodium azide.

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ABC-ASC11615-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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