IL-15RA Antibody

ArtNr	ABC-ASC11616
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Primary
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Giri JG, Kumaki S, Ahdieh M, et al. Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. EMBO J. 1995; 14:3654-63. Bodnar A, Nizsaloczki E, Mocsar G, et al. A biophysical approach to IL-2 and IL-15 receptor function: localization, conformation and interactions. Immunol. Lett. 2008; 116:117-25. Lorenz HM, Hieronymus T, Grunke M, et al. Differential role for IL-2 and IL-15 in the inhibition of apoptosis in short-term activated human lymphocytes. Scand. J. Immunol. 1997; 45:660-9.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Manufacturer - Category	Primary Antibodies; Cell Biology; Metabolism; Signal Transduction; Interleukin signaling; Jak-STAT signaling KEGG; Intestinal immune network for IgA production
Manufacturer - Targets	IL15RA; Multiple isoforms of IL-15RA are known to exist.
Storage Conditions	IL-15RA antibody can be stored at 4? for three months and -20?, stable for up to one year.
Bio Background	IL-15RA Antibody: Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.
Clonality	Polyclonal
Gene Name	IL15RA
Reactivity	H, M, Rat
Calculated Molecular Weight	28233
Antigen Source	homo sapiens
Purification	IL-15RA Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	IL-15RA antibody can be used for detection of IL-15RA by Western blot at 1 - 2 µg/mL.
Positive Control	Human Small Intestine Tissue Lysate
Buffer	IL-15RA Antibody is supplied in PBS containing 0.02% sodium azide.

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Menge: 100 ug

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Lieferung vsl. bis 06.11.2025

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